Prognostic factors for survival in patients with colorectal liver metastases: experience of a single brazilian cancer center

Autor: Héber Salvador de Castro Ribeiro, Paulo Roberto Stevanato-Filho, Wilson Luiz da Costa Jr., Alessandro Landskron Diniz, Paulo Herman, Felipe José Fernández Coimbra
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Arquivos de Gastroenterologia, Vol 49, Iss 4, Pp 266-272 (2012)
Druh dokumentu: article
ISSN: 1678-4219
0004-2803
DOI: 10.1590/S0004-28032012000400007
Popis: CONTEXT: Liver metastases are a common event in the clinical outcome of patients with colorectal cancer and account for 2/3 of deaths from this disease. There is considerable controversy among the data in the literature regarding the results of surgical treatment and prognostic factors of survival, and no analysis have been done in a large cohort of patients in Brazil. OBJECTIVES: To characterize the results of surgical treatment of patients with colorectal liver metastases, and to establish prognostic factors of survival in a Brazilian population. METHOD: This was a retrospective study of patients undergoing liver resection for colorectal metastases in a tertiary cancer hospital from 1998 to 2009. We analyzed epidemiologic variables and the clinical characteristics of primary tumors, metastatic disease and its treatment, surgical procedures and follow-up, and survival results. Survival analyzes were done by the Kaplan-Meier method and the log-rank test was applied to determine the influence of variables on overall and disease-free survival. All variables associated with survival with P
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