Efficacy and Safety of Mecobalamin Combined with Prokinetic Agents in the Treatment of Diabetic Gastroparesis: A Meta-Analysis

Autor: Jia Yao, Bo Peng, Xia yu Gong, Xiaoyan Shi, Simin Fan, Qiu Chen
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Iranian Journal of Public Health, Vol 50, Iss 11 (2021)
Druh dokumentu: article
ISSN: 2251-6085
2251-6093
Popis: Background: The aim of the present study was to systematically review the efficacy and safety of mecobalamin combined with prokinetic agents in diabetic gastroparesis (DGP). Methods: A variety of databases were searched from inception to Nov 2, 2018. RCTs of mecobalamin combined with prokinetic agents group (experimental group) versus prokinetic agents only group (control group) in DGP were included. RevMan 5.3 and Stata 12.0 were used to perform the meta-analysis. Finally, 24 RCTs with 1,878 patients were included. Results: The total efficacy rate was significantly higher in the experimental group (mecobalamin combined with prokinetic drugs) compared with the control group (prokinetic drugs alone) (P
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