| Autor: |
Suceena Alexander, Santosh Varughese, Rajanbabu Franklin, Sanjeet Roy, Grace Rebekah, Vinoi George David, Anjali Mohapatra, Anna T. Valson, Shibu Jacob, Pradeep Mathew Koshy, Gautham Rajan, Mohamed R. Daha, John Feehally, Jonathan Barratt, George T. John |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Kidney International Reports, Vol 6, Iss 2, Pp 414-428 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2468-0249 |
| DOI: |
10.1016/j.ekir.2020.11.026 |
| Popis: |
Introduction: Glomerular Research And Clinical Experiments–IgA Nephropathy in Indians (GRACE-IgANI) is the first prospective South Asian IgAN cohort with protocolized follow-up and extensive biosample collection. Here we report the baseline clinical, biochemical, and histopathologic characteristics of GRACE IgANI and calculate baseline risk of progression for the cohort. Methods: 201 incident adults with kidney biopsy–proven primary IgAN were recruited into GRACE-IgANI between March 2015 and September 2017. As of April 30, 2020, the cohort had completed a median follow-up of 30 months (interquartile range [IQR] 16-39). Results: The commonest clinical presentation in GRACE IgANI was hypertension, with or without proteinuria, and nephrotic-range proteinuria was present in 34%, despite |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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