| Autor: |
Sivakumar Periasamy, Kristen A. Porter, Maninjay K. Atianand, Hongnga T. Le, Sarah Earley, Ellen B. Duffy, Matthew C. Haller, Heather Chin, Jonathan A. Harton |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/ncomms15564 |
| Popis: |
Pyrin-only proteins (POPs) are primate-specific negative regulators of inflammasome activation. Here the authors generate transgenic mice expressing POP2 under the control of the human promoter, and show that POP2 is important for balancing antibacterial inflammatory responsesin vivo. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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