| Autor: |
Elizabeth M. Kass, Pei Xin Lim, Hildur R. Helgadottir, Mary Ellen Moynahan, Maria Jasin |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/ncomms13241 |
| Popis: |
Mutations in homology-directed repair genes likeBRCA2are linked to breast cancer susceptibility. Here the authors generate mice with an inducible DNA break-reporter system and see high levels of homology-directed repair in proliferative mammary tissue and a general reliance on BRCA2 in various tissues. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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