5.1 ASSESSMENT OF THE ARTERIAL WALL BEHAVIOR ALONG THE COMMON CAROTID ARTERY AT THE LEVEL OF A PLAQUE ACCORDING TO ARTERIAL STIFFNESS GRADIENT

Autor: H. Beaussier, I. Masson, O. Naggara, D. Calvet, R. Joannides, E. Guegan-Massardier, E. Gérardin, E. Bozec, P. Boutouyrie, S. Laurent
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Artery Research, Vol 3, Iss 4 (2009)
Druh dokumentu: article
ISSN: 1876-4401
DOI: 10.1016/j.artres.2009.10.159
Popis: Background: We previously described longitudinal strain gradient named bending strain (BS), along the common carotid artery (CCA) with two distinct patterns (Paini, Stroke 2007, Beaussier, Hypertension 2008): Pattern A (larger radial strain at the plaque level than at adjacent CCA) and its opposite, Pattern B. Aim: To assess the role of change in CCA thickness (IMT) and medial diameter (D) during the cardiac cycle at the level of plaques according to functional patterns of BS. Method: 45 CCA were analysed at the level of the plaque in 26 patients. Mechanical parameters were measured at 128 sites on a 4 cm long CCA segment by an echotracking system (ArtLab®). Plaque composition was determined by magnetic resonance imaging (MRI). For each plaque, systolo(s)-diastolic(d) variation of IMT and D were calculated. We obtained ΔIMT ((IMTs - IMTd)/IMTd), ΔDiameter ((Ds - Dd)/Dd) and ratio R (ΔIMT/ΔD). Results: R did not significantly differ according to remodeling pattern neither to plaque composition. Plaques exhibiting Pattern B (n=25) were characterized by an R 73 % higher than plaques exhibiting Pattern A (n=20) (5.9 ± 3.0 versus 3.4 ± 1.6, p
Databáze: Directory of Open Access Journals
Externí odkaz: