| Autor: |
D. A. Leach, A. Mohr, E. S. Giotis, E. Cil, A. M. Isac, L. L. Yates, W. S. Barclay, R. M. Zwacka, C. L. Bevan, G. N. Brooke |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-021-24342-y |
| Popis: |
TMPRSS2 is regulated by androgen receptor signalling in the prostate, however it is unclear if blocking this signalling is beneficial in the context of SARS-CoV-2 lung infection. Here the authors show that antiandrogen treatment downregulates TMPRSS2 in the lung and reduces viral entry and infection. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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