Autor: |
Yan-Lin Yang, Yang Liu, Ran Gao, De-Jing Song, Yi-Min Zhou, Ming-Yue Miao, Wei Chen, Shu-Peng Wang, Yue-Fu Wang, Linlin Zhang, Jian-Xin Zhou |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
Annals of Intensive Care, Vol 13, Iss 1, Pp 1-13 (2023) |
Druh dokumentu: |
article |
ISSN: |
2110-5820 |
DOI: |
10.1186/s13613-023-01209-7 |
Popis: |
Abstract Background Assessment of the patient’s respiratory effort is essential during assisted ventilation. We aimed to evaluate the accuracy of airway pressure (P aw)-based indices to detect potential injurious inspiratory effort during pressure support (PS) ventilation. Methods In this prospective diagnostic accuracy study conducted in four ICUs in two academic hospitals, 28 adult acute respiratory failure patients undergoing PS ventilation were enrolled. A downward PS titration was conducted from 20 cmH2O to 2 cmH2O at a 2 cmH2O interval. By performing an end-expiratory airway occlusion maneuver, the negative P aw generated during the first 100 ms (P 0.1) and the maximal negative swing of P aw (∆P occ) were measured. After an end-inspiratory airway occlusion, P aw reached a plateau, and the magnitude of change in plateau from peak P aw was measured as pressure muscle index (PMI). Esophageal pressure was monitored and inspiratory muscle pressure (P mus) and P mus–time product per minute (PTPmus/min) were used as the reference standard for the patient’s effort. High and low effort was defined as P mus > 10 and 200 and |
Databáze: |
Directory of Open Access Journals |
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