| Autor: |
Ugo Françoise, Mathieu Nacher, Morgane Bourne-watrin, Loïc Epelboin, Camille Thorey, Magalie Demar, Jean-François Carod, Félix Djossou, Pierre Couppié, Antoine Adenis |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
International Journal of Infectious Diseases, Vol 132, Iss , Pp 26-33 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1201-9712 |
| DOI: |
10.1016/j.ijid.2023.03.048 |
| Popis: |
Objectives: The burden of histoplasmosis is as great as that of tuberculosis in Latin America and the attributable mortality is even higher. A better assessment of severity could help reduce mortality. Methods: From the French Guiana HIV-histoplasmosis database, we attempted to identify factors associated with 30-day death after antifungal drug initiation and constructed a prognostic score. We evaluated its discrimination performance using several resampling methods. Results: Of the 415 patients included, 56 (13.5%) died within 30 days of treatment. The fatality-associated factors were performance status ≥3, altered mental status, dyspnea, C-reactive protein ≥75 mg/l, hemoglobin |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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