Seroepidemiology of hepatitis B virus (HBV) and relationship to serum transaminase levels in Indian population
| Autor: | Manoj Kumar, Kumari Seema, Dinesh Kumar, Abhay Kumar, Ashok Kumar Sharma, Manju Boipai, Aysha Rani |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Journal of Family Medicine and Primary Care, Vol 13, Iss 6, Pp 2410-2415 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2249-4863 2278-7135 |
| DOI: | 10.4103/jfmpc.jfmpc_1746_23 |
| Popis: | Background: Hepatitis B virus (HBV) infection is a serious public health issue that must be addressed. Aim: The goal of this study was to investigate the correlation between serological status for hepatitis Be antigen (HBeAg)/anti-HBe, serum transaminase levels, and serum HBV-DNA in patients with chronic HBV infection. Methods: A retrospective observational study with 620 patients with persistent HBV infection (mean age, 36.35 years; 506 men) was conducted. All patients tested positive for hepatitis B surface antigen (HBsAg). Liver profile, HBeAg, and anti-HBe antibody tests were conducted for all patients. Additionally, serum HBV DNA was examined using a DNA assay in these individuals. Results: Of 620 patients, 114 (18.39%) were HBeAg-positive and 506 (81.61%) HBeAg-negative. A detectable level of HBV DNA was found in 89.79% of HBeAg-positive/anti-HBe negative patients compared to HBeAg-negative/anti-HBe positive carriers 33.69% (P value |
| Databáze: | Directory of Open Access Journals |
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