Effect of aqueous extract of the Vigna angularis in rats subjected to an experimental model of moderate chronic kidney disease

Autor: Nilo César do Vale Baracho, Natália Fechus Monteiro, Manuela Guedes Borges, Raíssa Robles de Moura Arguelho
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Acta Cirúrgica Brasileira, Vol 31, Iss 8, Pp 527-532 (2016)
Druh dokumentu: article
ISSN: 0102-8650
DOI: 10.1590/S0102-865020160080000005
Popis: ABSTRACT PURPOSE: To evaluate the effect of the aqueous extract of the Vigna angularis, popularly known as "Azuki beans", in rats subjected to an experimental model of moderate chronic kidney disease. METHODS: Thirty rats underwent two surgeries - Ormrod and Miller (1980) - to obtain Moderate Chronic Kidney Disease (CKD-M). The animals were randomized into 3 groups. Group 1 (Control): distilled water. Group 2 (Azuki): Vigna angularis 5% aqueous extract. Group 3 (Treatment): 10mg/kg of enalapril maleate. The rats received their respective treatments for 14 days. RESULTS: The treatment with azuki beans produced an increase in urine output from the second day until the end of the experiment compared to the Control groups (p
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