From optically pure pyridinium salts to some new dihydro-2H-oxazolo[3,2-a]pyridines

Autor: R.G. Moura, P.R. Batista, L.C. Ducati, J. Gruber, L.F. Yamaguchi, L. Marzorati
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Results in Chemistry, Vol 5, Iss , Pp 100820- (2023)
Druh dokumentu: article
ISSN: 2211-7156
DOI: 10.1016/j.rechem.2023.100820
Popis: Treatment of 2,4,6-triphenylpiridinium salts, bearing a chiral β-hydroxy alkyl N-substituent with diluted aqueous sodium hydroxide afforded four new dihydrooxazolo[3,2a]pyridines,as an almost equimolar mixture of diastereomers. However, a highly selective ring closure reaction was observed for the pyridium salt derived from (1S,2S)-(+)-2-amino-1-phenyl-1,3-propanediol.
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