Ultrasound-guided drug delivery in cancer

Autor:	Sayan Mullick Chowdhury, Taehwa Lee, Jürgen K. Willmann
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	Ultrasonography Drug delivery systems Cancer therapy Genetic therapy Microbubbles Medical technology R855-855.5
Zdroj:	Ultrasonography, Vol 36, Iss 3, Pp 171-184 (2017)
Druh dokumentu:	article
ISSN:	2288-5919 2288-5943
DOI:	10.14366/usg.17021
Popis:	Recent advancements in ultrasound and microbubble (USMB) mediated drug delivery technology has shown that this approach can improve spatially confined delivery of drugs and genes to target tissues while reducing systemic dose and toxicity. The mechanism behind enhanced delivery of therapeutics is sonoporation, the formation of openings in the vasculature, induced by ultrasound-triggered oscillations and destruction of microbubbles. In this review, progress and challenges of USMB mediated drug delivery are summarized, with special focus on cancer therapy.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/050eebe38ea84c669e1b78e016f6dbe5 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF