Autor: |
Luca Gozzi, Diletta Cozzi, Edoardo Cavigli, Chiara Moroni, Caterina Giannessi, Giulia Zantonelli, Olga Smorchkova, Ron Ruzga, Ginevra Danti, Elena Bertelli, Valentina Luzzi, Valeria Pasini, Vittorio Miele |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
Diagnostics, Vol 13, Iss 7, p 1360 (2023) |
Druh dokumentu: |
article |
ISSN: |
2075-4418 |
DOI: |
10.3390/diagnostics13071360 |
Popis: |
Lymphoproliferative lung diseases are a heterogeneous group of disorders characterized by primary or secondary involvement of the lung. Primary pulmonary lymphomas are the most common type, representing 0.5–1% of all primary malignancies of the lung. The radiological presentation is often heterogeneous and non-specific: consolidations, masses, and nodules are the most common findings, followed by ground-glass opacities and interstitial involvement, more common in secondary lung lymphomas. These findings usually show a prevalent perilymphatic spread along bronchovascular bundles, without a prevalence in the upper or lower lung lobes. An ancillary sign, such as a “halo sign”, “reverse halo sign”, air bronchogram, or CT angiogram sign, may be present and can help rule out a differential diagnosis. Since a wide spectrum of pulmonary parenchymal diseases may mimic lymphoma, a correct clinical evaluation and a multidisciplinary approach are mandatory. In this sense, despite High-Resolution Computer Tomography (HRCT) representing the gold standard, a tissue sample is needed for a certain and definitive diagnosis. Cryobiopsy is a relatively new technique that permits the obtaining of a larger amount of tissue without significant artifacts, and is less invasive and more precise than surgical biopsy. |
Databáze: |
Directory of Open Access Journals |
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