Autor: |
André Malanda, Pierre-Yves Abécassis, Pascal Barnéoud, Pascale Brunel, Véronique Taupin, Xavier Vigé, Dominique Lesuisse |
Jazyk: |
angličtina |
Rok vydání: |
2019 |
Předmět: |
|
Zdroj: |
Data in Brief, Vol 27, Iss , Pp - (2019) |
Druh dokumentu: |
article |
ISSN: |
2352-3409 |
DOI: |
10.1016/j.dib.2019.104057 |
Popis: |
This article describes the chemical synthesis, ADME and pharmacological properties and early safety pharmacology evaluation of a series of novel Nurr1/NOT agonist. It is meant as a support to an article recently published in Bioorganic and Medicinal chemistry Letters and entitled “Development of a novel NURR1/NOT agonist from hit to lead and candidate for the potential treatment of Parkinson's disease” [1] and presenting the discovery, scope and potential of these new ligands of these nuclear receptors. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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