Antidiabetic activity and phytochemical screening of extracts of the leaves of Ajuga remota Benth on alloxan-induced diabetic mice

Autor: Tadesse Bekele Tafesse, Ariaya Hymete, Yalemtsehay Mekonnen, Mekuria Tadesse
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: BMC Complementary and Alternative Medicine, Vol 17, Iss 1, Pp 1-9 (2017)
Druh dokumentu: article
ISSN: 1472-6882
DOI: 10.1186/s12906-017-1757-5
Popis: Abstract Background Ajuga remota Benth is traditionally used in Ethiopia for the management of diabetes mellitus. Since this claim has not been investigated scientifically, the aim of this study was to evaluate the antidiabetic effect and phytochemical screening of the aqueous and 70% ethanol extracts on alloxan-induced diabetic mice. Methods After acute toxicity test, the Swiss albino mice were induced with alloxan to get experimental diabetes animals. The fasting mean blood glucose level before and after treatment for two weeks in normal, diabetic untreated and diabetic mice treated with aqueous and 70% ethanol extracts were performed. Data were statistically evaluated by using Statistical Package for the Social Sciences software version 20. P-value
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