| Autor: |
Waffa S. El-Shimy, Basem I. El-Shafey, Hesham A. El-Sorougy, Eman Ali Abd El-Monem |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Egyptian Journal of Chest Disease and Tuberculosis, Vol 64, Iss 2, Pp 411-417 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
0422-7638 |
| DOI: |
10.1016/j.ejcdt.2015.02.001 |
| Popis: |
Background: Tumor markers were used in malignant pleural effusion with negative cytology. Aim of the work: The aim was to assess the value of serum and pleural levels of cyfra 21-1 (fragment of cytokeratin 19) and carcinoembryonic antigen (CEA) in the diagnosis of malignant pleural effusion. Patients and methods: This study was conducted on 48 patients divided into group I (benign effusion) and group II (malignant effusion). Chest X-ray P.A view, pleural fluid analysis and measurement of serum and pleural levels of CEA and cyfra 21-1 were done. Results: Serum and pleural levels of cyfra 21-1 and CEA were significantly increased in the malignant group and compared to other groups. Sensitivities of cyfra 21-1 and CEA in serum were 90.4 and 90.5 and in pleural fluid were 94.7 and 92.6, the specificities of cyfra 21-1 and CEA in serum were 86.9 and 83.5 and in pleural fluid were 89.3 and 85.8 but sensitivity of both cyfra 21-1 and CEA in serum and pleural fluid was 100 and specificities in serum and pleural fluid were 92.86 and 96.43. Conclusion: Measurement of cyfra 21-1 and CEA in serum and pleural fluid is helpful in differentiation between benign and malignant pleural effusions. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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