Novel Biomarkers, ST‐Elevation Resolution, and Clinical Outcomes Following Primary Percutaneous Coronary Intervention

Autor:	Jay S. Shavadia, Christopher B. Granger, Wendimagegn Alemayehu, Cynthia M. Westerhout, Thomas J. Povsic, Sean Van Diepen, Christopher Defilippi, Paul W. Armstrong
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	biomarkers microvascular reperfusion primary percutaneous coronary intervention ST‐elevation resolution ST‐segment–elevation myocardial infarction Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 13 (2020)
Druh dokumentu:	article
ISSN:	2047-9980 84101970
DOI:	10.1161/JAHA.120.016033
Popis:	Background Despite restoration of epicardial flow following primary percutaneous coronary intervention (PPCI), microvascular reperfusion as reflected by ST‐elevation resolution (ST‐ER) resolution remains variable and its pathophysiology remains unclear. Methods and Results Using principal component analyses, we explored associations between 91 serum biomarkers drawn before PPCI clustered into 14 pathobiologic processes (including NT‐proBNP [N‐terminal pro‐B‐type natriuretic peptide] as an independent cluster), and (1) ST‐ER resolution ≥50% versus
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/04c4ebf17d5b49f7ae841019705ebc6f Zobrazit plný text záznamu Plný text View record in DOAJ