A NEW ANTIEPILEPTIC DRUG — ZONEGRAN (ZONISAMIDE) — IN THE TREATMENT OF EPILEPSY (A REVIEW)
| Autor: | O. A. Pylaeva, K. Yu. Мukhin |
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| Jazyk: | ruština |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Русский журнал детской неврологии, Vol 7, Iss 2, Pp 13-34 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2073-8803 2412-9178 |
| DOI: | 10.17650/2073-8803-2012-7-2-13-34 |
| Popis: | Despite the considerable advances of epileptology drug-resistant epilepsies consist about 30% among all forms of epilepsy. Authors represent the review of the literature devoted to efficacy and tolerability of zonisamide in the treatment of drug-resistant epilepsy. The current review of studies devoted to efficacy and safety of a new antiepileptic drug zonisamide in the treatment of epilepsy is proposed. The mechanism of action and pharmacokinetic of zonisamide are described; the questions of efficacy and tolerability in the treatment of drug-resistant focal epilepsies and other types of seizures and forms of epilepsy are considered. The possibilities of the use of the drug in the treatment of comorbid disorders are considered |
| Databáze: | Directory of Open Access Journals |
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