Efficacy of Tamsulosin, Oxybutynin, and their combination in the control of double-j stent-related lower urinary tract symptoms
| Autor: | Miguel Maldonado-Avila, Leopoldo Garduño-Arteaga, Rene Jungfermann-Guzman, Hugo A. Manzanilla-Garcia, Emmanuel Rosas-Nava, Nestor Procuna-Hernandez, Alejandro Vela-Mollinedo, Luis Almazan-Treviño, Jose Guzman-Esquivel |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | International Brazilian Journal of Urology, Vol 42, Iss 3, Pp 487-493 (2016) |
| Druh dokumentu: | article |
| ISSN: | 1677-6119 1677-5538 |
| DOI: | 10.1590/S1677-5538.IBJU.2015.0186 |
| Popis: | ABSTRACT Introduction and objective Indwelling double J ureteral stents are used routinely in the resolution of ureteral obstruction caused by different etiologies. Evaluation of urinary symptoms related to double-J stent, indicate that these affect 73-90% of patients. We conducted a prospective, randomized study, to evaluate the efficacy of tamsulosin, oxybutinin and combination therapy in improving the urinary symptoms. Methods Patients who underwent ureteral stent placement after ureterolithotripsy (total 51), were randomized into three groups: Group I: Tamsulosin 0.4 mg. once per day(17 patients), Group II: Oxybutinin 5 mg. once per day (17 patients), Group III: Tamsulosin+ oxybutynin once per day (17 patients). All the groups received the drugs for three weeks and completed a Spanish validated Ureteral Stent Symptom Questionnaire (USSQ) at day 7 and 21. Results Repeated measures ANOVA showed mean urinary symptom index score was 22.3 vs. 15.5 in group three (p |
| Databáze: | Directory of Open Access Journals |
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