The effect of diabetes and the diabetogenic TBC1D4 p.Arg684ter variant on kidney function in Inuit in Greenland

Autor: Maria Overvad, Lars Jorge Díaz, Peter Bjerregaard, Michael Lynge Pedersen, Christina Viskum Lytken Larsen, Niels Grarup, Torben Hansen, Peter Rossing, Marit Eika Jørgensen
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: International Journal of Circumpolar Health, Vol 82, Iss 1 (2023)
Druh dokumentu: article
ISSN: 22423982
2242-3982
DOI: 10.1080/22423982.2023.2191406
Popis: ABSTRACTThe aim of this study was to examine the effect of diabetes and the diabetogenic TBC1D4 variant on kidney function in Greenland in a population-based setting. Health survey data and TBC1D4 genotypes from 5,336 Greenlanders were used to estimate odds ratios (ORs) of albuminuria (>30 mg/g creatinine) and chronic kidney disease (CKD, eGFR
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