| Autor: |
Cristhian F. Montenegro, Chad Skiles, Dillon J. Kuszmaul, Aaron Gouw, Kiril Minchev, Toby L. Chambers, Ulrika Raue, Todd A. Trappe, Scott Trappe |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Physiological Reports, Vol 12, Iss 13, Pp n/a-n/a (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2051-817X |
| DOI: |
10.14814/phy2.16052 |
| Popis: |
Abstract We previously observed lifelong endurance exercise (LLE) influenced quadriceps whole‐muscle and myofiber size in a fiber‐type and sex‐specific manner. The current follow‐up exploratory investigation examined myofiber size regulators and myofiber size distribution in vastus lateralis biopsies from these same LLE men (n = 21, 74 ± 1 years) and women (n = 7, 72 ± 2 years) as well as old, healthy nonexercisers (OH; men: n = 10, 75 ± 1 years; women: n = 10, 75 ± 1 years) and young exercisers (YE; men: n = 10, 25 ± 1 years; women: n = 10, 25 ± 1 years). LLE exercised ~5 days/week, ~7 h/week for the previous 52 ± 1 years. Slow (myosin heavy chain (MHC) I) and fast (MHC IIa) myofiber nuclei/fiber, myonuclear domain, satellite cells/fiber, and satellite cell density were not influenced (p > 0.05) by LLE in men and women. The aging groups had ~50%–60% higher proportion of large (>7000 μm2) and small ( |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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