Stochastic cost-effectiveness analysis on population benefits

Autor: Ermo Chen
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Cost Effectiveness and Resource Allocation, Vol 21, Iss 1, Pp 1-14 (2023)
Druh dokumentu: article
ISSN: 1478-7547
DOI: 10.1186/s12962-023-00488-y
Popis: Abstract Dealing with randomness is a crucial aspect that cost-effectiveness analysis (CEA) tools need to address, but existing stochastic CEA tools have rarely examined risk and return from the perspective of population benefits, concerning the benefits of a group of individuals but not just a typical one. This paper proposes a stochastic CEA tool that supports medical decision-making from the perspective of population benefits of risk and return, the risk-adjusted incremental cost-effectiveness ratio (ICER). The tool has a traditional form of ICER but uses the cost under a risk-adjusted expectation. Theoretically, we prove that the tool can provide medical decisions trimming that promote the risk-return level on population benefits within any intervention structure and can also serve as a criterion for the optimal intervention structure. Numerical simulations within a framework of mean–variance support the conclusions in this paper.
Databáze: Directory of Open Access Journals
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