5 Fluorouracil‐loaded biosynthesised gold nanoparticles for the in vitro treatment of human pancreatic cancer cell

Autor:	Senthil Kumar Chinnaiyan, Agnes Mary Soloman, Ramesh Kannan Perumal, Arun Gopinath, Madhan Balaraman
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	5FU‐G‐AuNPs suitability 5‐FU‐G‐AuNPs human pancreatic cancer cell green synthesis sunlight irradiation method 5‐Fluorouracil‐loaded GG Biotechnology TP248.13-248.65
Zdroj:	IET Nanobiotechnology, Vol 13, Iss 8, Pp 824-828 (2019)
Druh dokumentu:	article
ISSN:	1751-875X 1751-8741
DOI:	10.1049/iet-nbt.2019.0007
Popis:	In this study, green synthesis of gold nanoparticles (AuNPs) was performed by a sunlight irradiation method using the Borassus flabellifer fruit extract as a reducing agent. 5‐Fluorouracil (5‐FU)‐loaded GG capped AuNPs (5FU‐G‐AuNPs) was prepared. The nanoparticles was further characterised by UV‐visible spectra, particle size analysis, zeta potential, SAED, HRTEM, and XRD. The MTT assay results showed the suitability 5‐FU‐G‐AuNPs. In this study, 5‐FU‐G‐AuNPs exhibited potential cytotoxic and apoptotic effects on (MiaPaCa‐2) cell line.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/0477ed270ad1496a929cd825185d5db1 Zobrazit plný text záznamu Plný text View record in DOAJ