Correlation of initial serum lactic acid and base deficit with early mortality in patients with major thermal burns at a Kenyan Tertiary Hospital

Autor: Muriithi Eliud Kennedy, Nangole Ferdinand Wanjala, Mwangi Peter Wambugu, Ayieko Philip
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Burns Open, Vol 7, Iss 2, Pp 37-43 (2023)
Druh dokumentu: article
ISSN: 2468-9122
DOI: 10.1016/j.burnso.2023.03.004
Popis: Objective: To correlate initial serum lactic acid and base deficit (BD) levels with early mortality in major thermal burns. Methods: This was a prospective descriptive study conducted over 6 months at Kenyatta National Hospital (KNH), Nairobi, Kenya. Ninety consecutive patients with major thermal burns exceeding 20% of total body surface area (TBSA), who met other inclusion criteria participated. Biographic and clinical data were collected using a structured questionnaire. Blood samples were drawn at admission for arterial blood gas analysis (ABGAs) to obtain serum lactic acid and BD levels. Patients were followed up for 7 days at KNH Burns Unit. Results: Studied patients had burns from 21% to 100% TBSA. Majority, 54(60%), had burns between 21% and 50% TBSA. 55(61.1%) patients died within 7 days after admission. 38(69.1%) of these deaths occured within the initial 48 h. Both mean serum lactic acid (P
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