Development and Validation of an Assay Method for Ciprofloxacin Hydrochloride Determination in Combination Ear Drops

Autor:	Livia Uncu, Elena Donici, Vladimir Valica, Oxana Vislouh, Veaceslav Gonciar, Sergiu Parii
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	ciprofloxacin hydrochloride uv-vis spectrophotometric method ear drop validation Chemistry QD1-999 General. Including alchemy QD1-65
Zdroj:	Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, Vol 14, Iss 2, Pp 56-61 (2019)
Druh dokumentu:	article
ISSN:	1857-1727 2345-1688
DOI:	10.19261/cjm.2019.607
Popis:	A simple, precise and accurate UV-Vis spectrophotometric method has been developed and validated for the estimation of ciprofloxacin hydrochloride from combination ear drops with basil oil (Ocimum basilicum). The results of the validation of the method demonstrate that the developed method is simple, rapid, accurate and robust over the concentration range 2-10 μg/mL. The developed and validated UV-Vis spectrophotometric method ciprofloxacin hydrochloride could be included in the Analytical Quality Control documents of the combined ear drops containing ciprofloxacin hydrochloride within the concentration range of 2-10 μg/mL and volatile basil oil.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/045aa57764e84bbf8f29f9f0012fdfc4 Zobrazit plný text záznamu View record in DOAJ