Diurnal Preference and Grey Matter Volume in a Large Population of Older Adults: Data from the UK Biobank

Autor: Ray Norbury
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Circadian Rhythms, Vol 18, Iss 1 (2020)
Druh dokumentu: article
ISSN: 1740-3391
DOI: 10.5334/jcr.193
Popis: Eveningness (a diurnal preference for evening time) is associated with a number of negative health outcomes and risk and prevalence for psychiatric disorder. Our understanding of the anatomical substrates of diurnal preference, however, is limited. The current study used Voxel-Based Morphometry to compare grey matter volume in a large sample ('N' = 3730) of healthy adults determined by questionnaire to be either definite morning-type or definite evening-type. Eveningness was associated with increased grey matter volume in precuneus, brain regions implicated in risk and reward processing (bilateral nucleus accumbens, caudate, putamen and thalamus) and orbitofrontal cortex. These results indicate an anatomical-basis for diurnal preference which may underlie reported differences in behaviour and brain function observed in these individuals.
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