Nutrition and the Gut Microbiota in 10- to 18-Month-Old Children Living in Urban Slums of Mumbai, India

Autor: Samantha L. Huey, Lingjing Jiang, Marcus W. Fedarko, Daniel McDonald, Cameron Martino, Farhana Ali, David G. Russell, Shobha A. Udipi, Aparna Thorat, Varsha Thakker, Padmini Ghugre, R. D. Potdar, Harsha Chopra, Kripa Rajagopalan, Jere D. Haas, Julia L. Finkelstein, Rob Knight, Saurabh Mehta
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: mSphere, Vol 5, Iss 5 (2020)
Druh dokumentu: article
ISSN: 2379-5042
DOI: 10.1128/mSphere.00731-20
Popis: ABSTRACT In this cross-sectional study, we describe the composition and diversity of the gut microbiota among undernourished children living in urban slums of Mumbai, India, and determine how nutritional status, including anthropometric measurements, dietary intakes from complementary foods, feeding practices, and micronutrient concentrations, is associated with their gut microbiota. We collected rectal swabs from children aged 10 to 18 months living in urban slums of Mumbai participating in a randomized controlled feeding trial and conducted 16S rRNA sequencing to determine the composition of the gut microbiota. Across the study cohort, Proteobacteria dominated the gut microbiota at over 80% relative abundance, with Actinobacteria representation at
Databáze: Directory of Open Access Journals