Increase in Vitamin D but not Regulatory T Cells following Ultraviolet B Phototherapy of Patients with Atopic Dermatitis

Autor:	Stine Simonsen, Charlotte M. Bonefeld, Jacob P. Thyssen, Carsten Geisler, Lone Skov
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	nbUVB phototherapy atopic dermatitis 25-hydroxyvitamin D regulatory T cells filaggrin Dermatology RL1-803
Zdroj:	Acta Dermato-Venereologica, Vol 99, Iss 2, Pp 139-145 (2018)
Druh dokumentu:	article
ISSN:	0001-5555 1651-2057 00015555
DOI:	10.2340/00015555-3050
Popis:	This study investigated serum 25-hydroxyvitamin D (25(OH)D) concentrations and circulating regulatory T cells in patients with atopic dermatitis receiving narrow-band ultraviolet B (nbUVB) phototherapy. Thirty adult patients with atopic dermatitis were included. Blood samples were collected at baseline and at weeks 2 and 4 of nbUVB phototherapy. Skin biopsies were taken at baseline and at week 4. Serum 25(OH)D concentrations increased significantly following nbUVB phototherapy (estimate of change from baseline to week 2: 32.00 nmol/l, confidence interval (CI) 20.48–43.52, p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/043c896dcd8a46aabfa523d9948e66cd Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF