Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation

Autor: Jonathan Latham, Jean-Marc Henry, Humera H. Sharif, Binuraj R. K. Menon, Sarah A. Shepherd, Michael F. Greaney, Jason Micklefield
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms11873
Popis: Biocatalysis and metal catalysis often provide complimentary reactivities and selectivities. Here, the authors exploit the regioselectivity of an enzymatic C–H activation followed by palladium catalysed carbon-carbon bond formation in one pot, with membrane compartmentalization used to isolate the two chemistries.
Databáze: Directory of Open Access Journals