A cohort study of hospitalized adult dengue patients with fatality in Taiwan: The elderly and febrile characteristics matter for prognosis

Autor: Tsung-Hang Kuo, Chia-Chang Chuang, Chin-Chung Tseng, Ming-Yuan Hong, Sheng-Hsiang Lin
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Asian Pacific Journal of Tropical Medicine, Vol 13, Iss 7, Pp 301-307 (2020)
Druh dokumentu: article
ISSN: 2352-4146
1995-7645
92162339
DOI: 10.4103/1995-7645.285829
Popis: Objective: To identify the febrile characteristics and clinical presentations associated with fatality in hospitalized adult patients with dengue virus (DENV) infections. Methods: A total of 289 adult hospitalized patients with laboratory-confirmed DENV infections were examined, of which 22 were fatal and 267 were non-fatal. A comparison of the clinical and laboratory characteristics was retrospectively conducted of the deceased and surviving individuals. Multivariate logistic regression and receiver operating characteristic curve analysis were performed to identify predictors of fatality. Results: Fatal patients exhibited significantly more comorbidities, particularly renal and cardiac comorbidities, and they were, in general, older than control individuals (P
Databáze: Directory of Open Access Journals