| Autor: |
Bengü Gülhan Aydın, Gamze Küçükosman, Özcan Pişkin, Necla Gülçek, Rahşan Dilek Okyay, Hilal Ayoğlu |
| Jazyk: |
English<br />Turkish |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Cukurova Medical Journal, Vol 46, Iss 4, Pp 1614-1623 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2602-3040 |
| DOI: |
10.17826/cumj.986099 |
| Popis: |
Purpose: This study aimed to evaluate the effect of controlled hypotension on cerebral oxygen saturation and postoperative cognitive dysfunction (POCD) in patients undergoing nasal surgery. Materials and Methods: Forty patients were randomized by a sealed envelope method into two drug groups: esmolol (Group E, n=20) or nitroglycerin (Group N, n=20) administration prior to surgical incision. The cognitive functions of the patients were evaluated by the Mini-Mental State Examination Test 1 day before and 1 day after the operation. Regional oxygen saturation was monitored with near-infrared spectroscopy to detect cerebral desaturation. Results: The desired mean arterial blood pressure (50-65 mmHg) could be achieved in all groups. A decline in cognitive function occured in 16 patients (40%) at the 24th postoperative hour. There was no statistically significant difference between the groups in terms of POCD. There was a significant relationship between POCD and cerebral desaturation status. Conclusion: Cerebral desaturation seen during hypotensive anesthesia may cause early POCD development, therefore we think that close cerebral and hemodynamic monitoring during hypotensive anesthesia may preserve cognitive functions. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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