Hyperendemicity, heterogeneity and spatial overlap of leprosy and cutaneous leishmaniasis in the southern Amazon region of Brazil

Autor: Amanda Gabriela de Carvalho, João Gabriel Guimarães Luz, João Victor Leite Dias, Anuj Tiwari, Peter Steinmann, Eliane Ignotti
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Geospatial Health, Vol 15, Iss 2 (2020)
Druh dokumentu: article
ISSN: 1827-1987
1970-7096
DOI: 10.4081/gh.2020.892
Popis: Neglected tropical diseases characterized by skin lesions are highly endemic in the state of Mato Grosso, Brazil. We analyzed the spatial distribution of leprosy and Cutaneous Leishmaniasis (CL) and identified the degree of overlap in their distribution. All new cases of leprosy and CL reported between 2008 and 2017 through the national reporting system were included in the study. Scan statistics together with univariate Global and Local Moran’s I were employed to identify clusters and spatial autocorrelation for each disease, with the spatial correlation between leprosy and CL measured by bivariate Global and Local Moran’s I. Finally, we evaluated the demographic characteristics of the patients. The number of leprosy (N = 28,204) and CL (N = 24,771) cases in Mato Grosso and the highly smoothed detection coefficients indicated hyperendemicity and spatial distribution heterogeneity. Scan statistics demonstrated overlap of high-risk clusters for leprosy (RR = 2.0; P
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