Superficial intraventricular surface siderosis brain

Autor: Edlira Harizi, MD, Kledisa Shemsi, MD, Ilir Ahmetgjekaj, MD, PhD, Anusha Parisapogu, MBBS, Keti Mamillo, MD, Fjolla Hyseni, MD, PhDc, Simmy Lahori, MBBS, Kampa Prathima, MBBS, Chandalji Naik Banavath, MBBS, Zaina Syed, MD, Srikrishnan Pichuthirumalai, MBBS, Juna Musa, MD, Jasmine Saini, MD, Arieta Hasani Alidema, MD, Valon Vokshi, MD, Mohammad Abubaker Siddique, MBBS
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Radiology Case Reports, Vol 17, Iss 11, Pp 4152-4155 (2022)
Druh dokumentu: article
ISSN: 1930-0433
DOI: 10.1016/j.radcr.2022.08.022
Popis: Superficial siderosis of the central nervous system is a chronic condition characterized by hemosiderin deposition in the brain and spinal cord. It's diagnosed by brain MRI. It can be caused by low-grade extravasation of blood into the subarachnoid space of the brain. There are 2 types of superficial siderosis cortical and infratentorial. Although asymptomatic in many cases; Cerebellar-predominant siderosis, a subtype of infratentorial, can affect hearing, gait, and even muscles. In this report, we present a case of a 51-year old female with complaints of hearing loss, unsteadiness in his lower limb, and spastic paresis. During MRI neuroimaging, we noticed findings of hypointensity areas within the brainstem and cerebellum, probably due to hemosiderin deposition. Based on the MRI findings, the patient was diagnosed with superficial siderosis. The patient was started on deferiprone and followed for the consecutive 18 months. Moderate improvement of the hearing loss and ataxia was noted while no change in muscle force. However, the repetitive MRI did not reveal any changes compared to the previous one.
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