Visualizing RNA conformational and architectural heterogeneity in solution

Autor: Jienyu Ding, Yun-Tzai Lee, Yuba Bhandari, Charles D. Schwieters, Lixin Fan, Ping Yu, Sergey G. Tarosov, Jason R. Stagno, Buyong Ma, Ruth Nussinov, Alan Rein, Jinwei Zhang, Yun-Xing Wang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-023-36184-x
Popis: RNA conformational heterogeneity is important to diverse functions. Here, the authors use AFM to directly visualize individual RNA molecules that are in various conformational states under near physiological solution conditions for the first time.
Databáze: Directory of Open Access Journals