| Autor: |
Mayank Sharma, Rajesh Sharma, Dinesh Kumar Jain |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Scientifica, Vol 2016 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2090-908X |
| DOI: |
10.1155/2016/8525679 |
| Popis: |
Oral administration is the most convenient route among various routes of drug delivery as it offers high patient compliance. However, the poor aqueous solubility and poor enzymatic/metabolic stability of drugs are major limitations in successful oral drug delivery. There are several approaches to improve problems related to hydrophobic drugs. Among various approaches, nanotechnology based drug delivery system has potential to overcome the challenges associated with the oral route of administration. Novel drug delivery systems are available in many areas of medicine. The application of these systems in the treatment of hypertension continues to broaden. The present review focuses on various nanocarriers available in oral drug administration for improving solubility profile, dissolution, and consequently bioavailability of hydrophobic antihypertensive drugs. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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