Magnetic field and nuclear spin influence on the DNA synthesis rate

Autor: Sergey V. Stovbun, Dmitry V. Zlenko, Alexander A. Bukhvostov, Alexander S. Vedenkin, Alexey A. Skoblin, Dmitry A. Kuznetsov, Anatoly L. Buchachenko
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-022-26744-4
Popis: Abstract The rate of a chemical reaction can be sensitive to the isotope composition of the reactants, which provides also for the sensitivity of such “spin-sensitive” reactions to the external magnetic field. Here we demonstrate the effect of the external magnetic field on the enzymatic DNA synthesis together with the effect of the spin-bearing magnesium ions ( $$^{25}$$ 25 Mg). The rate of DNA synthesis monotonously decreased with the external magnetic field induction increasing in presence of zero-spin magnesium ions ( $$^{24}$$ 24 Mg). On the contrary, in the presence of the spin-bearing magnesium ions, the dependence of the reaction rate on the magnetic field induction was non-monotonous and possess a distinct minimum at 80–100 mT. To describe the observed effect, we suggested a chemical scheme and biophysical mechanism considering a competition between Zeeman and Fermi interactions in the external magnetic field.
Databáze: Directory of Open Access Journals
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