Assessment of hospitalizations of patients after intoxication with organophosphates used in agriculture

Autor: Anna Katarzyna Orzeł, Wojciech Flieger, Dominika Szlichta, Barbara Terpiłowska, Michał Terpiłowski, Zbigniew Orzeł, Michał Tchórz, Jarosław Szponar
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Annals of Agricultural and Environmental Medicine, Vol 29, Iss 1, Pp 143-148 (2022)
Druh dokumentu: article
ISSN: 1232-1966
1898-2263
DOI: 10.26444/aaem/145769
Popis: Introduction Clinical manifestation of organophosphates toxicity may be differentiate and include cholinergic toxidrome, intermediate syndrome, OP-induced delayed polyneuropathy to chronic OP-induced neuropsychiatric disorder (OPIDN). Patients symptoms, along with decrease in cholinesterase serum level, determines the possible diagnosis of organophosphate poisoning. Objective The aim of the study was to present the clinical manifestation and cholinesterase level changes in intoxication with organophosphorus compounds in patients. Material and methods A data base was created by analysis of the hospital documents of 34 patients hospitalized due to organophosphate intoxication. Statistical analysis involved frequency tables with percentage values, the application of non-parametric Chi-square test and parametric t-Student test (with homogeneity of variance Levine test). The level of static significance was set to p=0.05. Results In fatal hospitalizations (20.6%), cholinesterase level was significantly lower (265.87 U/l) than in other patients (4254.78 U/l; p
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