Clinical application of mineralocorticoid receptor antagonists in chronic heart failure

Autor:	MG Bubnova
Jazyk:	ruština
Rok vydání:	2014
Předmět:	хроническая сердечная недостаточность инфаркт миокарда альдостерон антагонисты минералокортикоидных рецепторов эплеренон chronic heart failure myocardial infarction aldosterone mineralocorticoid receptor antagonists eplerenone Medicine
Zdroj:	Медицинский совет, Vol 0, Iss 12, Pp 70-80 (2014)
Druh dokumentu:	article
ISSN:	2079-701X 2658-5790
DOI:	10.21518/2079-701X-2014-12-70-80
Popis:	The review of literature discusses pathogenetic aspects of chronic heart failure and post-infarction remodelling in the heart. The focus is on the role of neurohormonal activation and the important role of aldosterone. There is data on the efficacy and safety of drugs belonging to mineralocorticoid receptor antagonists obtained in the course of randomized clinical trials. Different aspects of clinical application of the selective aldosterone receptor blocker eplerenone are emphasized. The application in clinical practice is supported by research findings.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/03b2820fe788499d91b086eadcddfc0f Zobrazit plný text záznamu View record in DOAJ