Obstetric Thromboprophylaxis: The Swedish Guidelines

Autor: Pelle G. Lindqvist, Margareta Hellgren
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Advances in Hematology, Vol 2011 (2011)
Druh dokumentu: article
ISSN: 1687-9104
1687-9112
DOI: 10.1155/2011/157483
Popis: Obstetric thromboprophylaxis is difficult. Since 10 years Swedish obstetricians have used a combined risk estimation model and recommendations concerning to whom, at what dose, when, and for how long thromboprophylaxis is to be administrated based on a weighted risk score. In this paper we describe the background and validation of the Swedish guidelines for obstetric thromboprophylaxis in women with moderate-high risk of VTE, that is, at similar or higher risk as the antepartum risk among women with history of thrombosis. The risk score is based on major risk factors (i.e., 5-fold increased risk of thromboembolism). We present data on the efficacy of the model, the cost-effectiveness, and the lifestyle advice that is given. We believe that the Swedish guidelines for obstetric thromboprophylaxis aid clinicians in providing women at increased risk of VTE with effective and appropriate thromboprophylaxis, thus avoiding both over- and under-treatment.
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