Clinical Features of Cutaneous Leishmaniasis and Direct PCR-Based Identification of Parasite Species in A New Focus in Southeast of Iran

Autor: A Fazaeli, B Fouladi, SM Hashemi-Shahri, I Sharifi
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: Iranian Journal of Public Health, Vol 37, Iss 3, Pp 44-51 (2008)
Druh dokumentu: article
ISSN: 2251-6085
Popis: "nBackground: To clinically characterize the cutaneous leishmaniasis and identify the causative parasite species in Mirjaveh, an important geographical region across the border of Iran-Pakistan at Southeast of Iran."nMethods: A number of 116 patients during a year since March 2005 to April 2006, subjected to the study. Clinical infor­mation collected and scrapings were taken from cutaneous lesions and used for microscopic examination, NNN cultivation and kinetoplast DNA-PCR amplification."nResults: The cases comprised of 48 males and 68 females, 84 (72.4%) Iranians and 32 (27.6%) non-Iranians. They aged between 2 months to 68 years with the most affection of children, 0-10 years (55.2%). The patients presented a total of 248 active lesions with an average of 2.14. The ulcers distributed mostly on upper extremity (42.3%) then on face (32.7%), fol­lowed by lower extremity (20.6%) and other parts (4.4%). The majority of ulcers stated to be developed rapidly,
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