Combating Drug-Resistant Mutants of Anaplastic Lymphoma Kinase with Potent and Selective Type‑I1/2 Inhibitors by Stabilizing Unique DFG-Shifted Loop Conformation

Autor: Peichen Pan, Huidong Yu, Qinglan Liu, Xiaotian Kong, Hu Chen, Jiean Chen, Qi Liu, Dan Li, Yu Kang, Huiyong Sun, Wenfang Zhou, Sheng Tian, Sunliang Cui, Feng Zhu, Youyong Li, Yong Huang, Tingjun Hou
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: ACS Central Science, Vol 3, Iss 11, Pp 1208-1220 (2017)
Druh dokumentu: article
ISSN: 2374-7943
2374-7951
DOI: 10.1021/acscentsci.7b00419
Databáze: Directory of Open Access Journals