Hyperthermia treatment advances for brain tumors

Autor: Georgios P. Skandalakis, Daniel R. Rivera, Caroline D. Rizea, Alexandros Bouras, Joe Gerald Jesu Raj, Dominique Bozec, Constantinos G. Hadjipanayis
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: International Journal of Hyperthermia, Vol 37, Iss 2, Pp 3-19 (2020)
Druh dokumentu: article
ISSN: 0265-6736
1464-5157
02656736
DOI: 10.1080/02656736.2020.1772512
Popis: Hyperthermia therapy (HT) of cancer is a well-known treatment approach. With the advent of new technologies, HT approaches are now important for the treatment of brain tumors. We review current clinical applications of HT in neuro-oncology and ongoing preclinical research aiming to advance HT approaches to clinical practice. Laser interstitial thermal therapy (LITT) is currently the most widely utilized thermal ablation approach in clinical practice mainly for the treatment of recurrent or deep-seated tumors in the brain. Magnetic hyperthermia therapy (MHT), which relies on the use of magnetic nanoparticles (MNPs) and alternating magnetic fields (AMFs), is a new quite promising HT treatment approach for brain tumors. Initial MHT clinical studies in combination with fractionated radiation therapy (RT) in patients have been completed in Europe with encouraging results. Another combination treatment with HT that warrants further investigation is immunotherapy. HT approaches for brain tumors will continue to a play an important role in neuro-oncology.
Databáze: Directory of Open Access Journals
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