Do clinical features relate to theory of mind, empathy and 2D:4D in schizophrenia?
Autor: | Özge Akgül, Onur Küçükçoban, Tolga Binbay, Emre Bora, Köksal Alptekin, Berna Binnur Akdede |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: | |
Zdroj: | Psychiatry and Clinical Psychopharmacology, Vol 27, Iss 4, Pp 380-385 (2017) |
Druh dokumentu: | article |
ISSN: | 2475-0573 2475-0581 24750573 |
DOI: | 10.1080/24750573.2017.1373725 |
Popis: | OBJECTIVE: Digit ratios may be accepted as an indicator of level of prenatal androgen exposure during the fetal developmental period. Female-typical digit ratios have been suggested to be associated with better mentalizing and empathic abilities in general population. Recently, a number of studies have investigated the ratio of hand’s second and fourth digit fingers (2D:4D) in schizophrenia. The aim of this study was to investigate the hypothesis that positive symptoms are related to female-biased 2D:4D and relatively less impaired social cognition in schizophrenia, negative dimension is related to male-biased 2D:4D ratio and more pronounced deficits in social cognition. METHOD: The study was carried out in 48 patients with schizophrenia and 48 healthy controls. Patients were evaluated by Positive and Negative Syndrome Scale (PANSS). A digital caliper was used to measure 2D:4D finger lengths and social cognitive abilities were assessed using the Empathy Quotient (EQ) test and Reading Mind in the Eyes Test (RMET). RESULTS: Patients with schizophrenia had increased left 2D:4D finger lengths and showed poor theory of mind (ToM) and empathic abilities compared to healthy controls (p |
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