Therapeutic plasma exchange: A life-saving modality in Wegener's granulomatosis

Autor:	Archana Solanki, Ashutosh Singh, Abhishek Chauhan, Tulika Chandra, D Himanshu
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	antineutrophil cytoplasmic antibodies immunosuppression therapeutic plasma exchange wegener's granulomatosis Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Asian Journal of Transfusion Science, Vol 14, Iss 2, Pp 203-205 (2020)
Druh dokumentu:	article
ISSN:	0973-6247 1998-3565
DOI:	10.4103/ajts.AJTS_89_19
Popis:	We report a case of Wegener's granulomatosis (WG) who very well responded to the combination strategy of therapeutic plasma exchange (TPE) and immunosuppression. The patient was a 38-year-old female, diagnosed with severe form of WG. A total of seven cycles was performed with 1.3 total plasma volumes (TPVs) on every alternate day. Standard induction therapy was also started that comprised of a combination of 500 mg intravenous (i.v.) cyclophosphamide and methylprednisolone 1 g slow i.v. daily for 3 days followed by oral prednisolone 60 mg daily for 4 weeks. After seven cycles of TPE, the patient improved and hence TPE was stopped.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/036d00634a634ac18733ba11074eeebf Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF