Hormonal changes aggravate premenstrual tension syndrome in obese women and beneficial roles of combined pharmacological therapies: A randomized controlled trial
Autor: | Hytham Mahmoud Abdel-Latif, Amal Yaseen Zaman, Rawan Bafail, Raghad A. Mostafa, Mohamed M. Mabrouk, Hanan Yousef Aly, Nivin Baiomy, Amira A. Abdelnaby, Hend Mohamed Hussein, Samer A. El-Sawy, Salah Mohamed El Sayed, Hussam Baghdadi, Alfarazdeg Ageed Saad, Abdelfattah Alayoubi, Reda S. Yousef |
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Jazyk: | angličtina |
Rok vydání: | 2024 |
Předmět: | |
Zdroj: | SVU - International Journal of Medical Sciences, Vol 7, Iss 2, Pp 313-324 (2024) |
Druh dokumentu: | article |
ISSN: | 2735-427X 2636-3402 |
DOI: | 10.21608/svuijm.2024.304506.1933 |
Popis: | Background: The recurring psychological, behavioural, and physical symptoms of premenstrual tension syndrome (PTS) are related to the luteal phase of the menstrual cycle. Its development may be influenced by hormonal influences. Objectives: To investigate the effects of catecholamines on PTS and possible improvements upon using pharmacological treatments. Patients and methods: After agreement of participants and ethical committee approval, this randomized controlled trial enrolled 60 obese women with PTS who were split into younger (18-39 years) and older (40-48 years) age groups in comparison to an age-matched healthy control group. All of the study participants' serum levels of adrenaline (epinephrine), and norepinephrine were measured. Utilizing pertinent rating scales, a few psychosomatic PTS symptoms (headache, backache, and stomach bloating) were also assessed. Results: Compared to the control group, obese women with PTS had significantly higher serum levels of adrenaline, and noradrenaline (p |
Databáze: | Directory of Open Access Journals |
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