| Autor: |
Tianchen Zhao, Yuta Tani, Chieko Makino-Okamura, Morihito Takita, Chika Yamamoto, Eiki Kawahara, Toshiki Abe, Sota Sugiura, Hiroki Yoshimura, Taiga Uchiyama, Isato Yamazaki, Harumichi Ishigame, Takaharu Ueno, Kazu Okuma, Masatoshi Wakui, Hidehiro Fukuyama, Masaharu Tsubokura |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Frontiers in Immunology, Vol 15 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1664-3224 |
| DOI: |
10.3389/fimmu.2024.1337520 |
| Popis: |
This study investigates the neutralizing activity against the XBB1.5 variant and the ancestral strain in a population post-bivalent vaccination using a pseudo virus assay validated with authentic virus assay. While bivalent booster vaccination and past infections enhanced neutralization against the XBB 1.5 strain, individuals with comorbidities showed reduced responses. The study suggests the need for continuous vaccine updates to address emerging SARS-CoV-2 variants and highlights the importance of monitoring real-world immune responses. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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