| Autor: |
Nuria Valdés, Ana Romero, Estrella Diego, María Calatayud, Cristina Lamas, Marta Araujo-Castro, Cristina Álvarez-Escolá, José A. Díaz, Victoria Alcázar, Julia Sastre, Rosa Martínez, Josep Oriola, Miguel Paja, Paula Sánchez-Sobrino, Isabel Salinas, José María Recio-Córdova, Elena Navarro, María Dolores Chiara, Luis Castaño, Anna Casterás |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Frontiers in Endocrinology, Vol 15 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1664-2392 |
| DOI: |
10.3389/fendo.2024.1427821 |
| Popis: |
IntroductionHistorically, Multiple Endocrine Neoplasia type 1 (MEN1)-related pituitary adenomas (PAs) were considered more aggressive and treatment-resistant than sporadic PAs. However, recent studies suggest similarities in their behavior. This study aimed to evaluate the long-term outcomes of MEN1 PAs and identify predictive factors.MethodsNationwide multicenter retrospective cohort study of MEN1-related PAs with a minimum 1-year follow-up, collecting patient demographics, germline MEN1 pathogenic variants (PV), PA size, secretory profile, radiological characteristics, treatments, and outcomes.ResultsWe analyzed 84 PAs, 69%in females and 31% in males (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
