Clinical Characteristics and Long-Term Prognosis of Elderly Valvular Heart Disease Patients with Diabetes Mellitus: Five-Year Experience from a Single-Center Study of Southern China

Autor: Yuan-Feng Liang, Feier Song, Huixia Liu, Jian Liu, Yu-Yuan Zhang, Wei-Dong Lin, Hong-Tao Liao, Hui-Ming Guo, Gary Tse, Fang-Zhou Liu, Zhanyi Lin
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Cardiology Research and Practice, Vol 2021 (2021)
Druh dokumentu: article
ISSN: 2090-0597
DOI: 10.1155/2021/2558639
Popis: Background. Diabetes mellitus (DM) is a prognostic marker in elderly patients with cardiovascular diseases, but its predictive value in elderly valvular heart disease (VHD) patients is unclear. This study aimed to investigate the effect of DM on the long-term outcome of elderly VHD patients. Methods. This single-center, observational study enrolled patients aged 65 and older consecutively with confirmed VHD using echocardiography. Patients, divided into the DM group and non-DM group, were followed up for major adverse cardiac and cerebrovascular events (MACCEs), including all-cause death, ischemic stroke, and heart failure rehospitalization. Results. Our study consisted of 532 patients over a median follow-up of 52.9 months. Compared with the non-DM group (n = 377), the DM group (n = 155) had higher incidences of ischemic stroke (25.2% vs. 13.5%, P=0.001), heart failure rehospitalization (37.4% vs. 20.7%, P
Databáze: Directory of Open Access Journals
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