Defense reaction induced by a metabotropic glutamate receptor agonist microinjected into the dorsal periaqueductal gray of rats

Autor: M.L. Molchanov, F.S. Guimarães
Jazyk: angličtina
Rok vydání: 1999
Předmět:
Zdroj: Brazilian Journal of Medical and Biological Research, Vol 32, Iss 12, Pp 1533-1537 (1999)
Druh dokumentu: article
ISSN: 0100-879X
1414-431X
DOI: 10.1590/S0100-879X1999001200013
Popis: The behavioral effects of trans-(±)-1-amino-1,3-cyclopentanedicarboxylic acid (t-ACPD), a metabotropic glutamate receptor (mGluR) agonist, or 0.9% (w/v) saline, injected into the dorsal periaqueductal gray (DPAG), was investigated. Male Wistar rats showed defense reactions characterized by jumps toward the top edges of the cages (saline = 0 vs t-ACPD = 6.0, medians P
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